Specially formulated with simulated pheromones to calm your nervous dog. Helps reduce separation anxiety when you are away and soothe during stressful moments, such as thunderstorms, loud noises, visits to the vet, training and crating or moving to a new home. Plugs into wall outlet to dispense evenly throughout an area of up to 650 sq. ft. for up to four weeks. Diffuser holds 48 ml., available in refills.