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RIFAMPIN

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Why has my veterinarian prescribed Rifampin for my dog?

Rifampin is an antibiotic used to treat bacterial infections caused by Rhodococcus, Mycobacteria and Staphylococci.  Rifampin has antifungal activity when combined with other antifungal agents and may be used to treat infections such as histoplasmosis or aspergillosis.

How do I give Rifampin to my dog?

  • Give this medication to your dog as directed by your veterinarian. READ THE LABEL CAREFULLY.
  • Wear disposable gloves when giving this medication to dogs.  This medication may stain skin and cause rashes in people.
  • If using the liquid form of this medication, shake well before measuring the dose and measure the dose with reasonable care.
  • Give this medication on an empty stomach.
  • Give this medication for as long as prescribed by your veterinarian, even if it appears your dog is feeling better. This will help to ensure the infection is completely cleared up.
  • DO NOT give your dog more medicine than directed.
  • DO NOT give the medicine more often than directed.
  • Try not to miss giving any doses.

What if I miss giving a dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your dog two doses at once.

How do I store Rifampin?

  • Keep this medicine out of reach of children.
  • Store capsules and tablets in a cool, dry place at room temperature. Store away from heat and direct sunlight.
  • The liquid medication should be stored in the refrigerator.
  • Do not store this medicine in the bathroom, near the kitchen sink or in other damp places. The medicine may break down if exposed to heat or moisture.

Are there any potential side effects?

  • Rifampin may cause urine, tears, sweat and saliva to turn a red-orange color.  This is normal and does not harm the animal.
  • Your dog may develop a rash or a stomach upset. Contact your veterinarian if these effects are troublesome.
  • Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Are there any possible drug interactions?

  • Make sure to tell your veterinarian what other medication or supplements you are giving your dog.
  • Quite often your veterinarian may prescribe two different medications, even if a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.
  • The following drugs can potentially interact with rifampin:  propranolol, quinidine, dapsone, chloramphenicol, corticosteroids, oral anticoagulants, ketoconazole, benzodiazepines and barbiturates.
  • Contact your veterinarian if your dog experiences any unusual reactions when different medications are given together.

REMEMBER!  READ THE LABEL.


Based on material written by Rita Ozolins, B.Sc., Phm. and modified with permission from Lifelearn Inc.
© Copyright 2005 Lifelearn Inc.



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